Neural crest-related stem cells of oral origins in vitro and used in osteoporotic sheep model for being investigated due to therapeutic effects in alveolar bone regeneration

Neural crest-related stem cells (NCSC) have great promise in the field of regenerative medicine due to their differentiation potential into several lineages. Besides the periodontium, and root surfaces of extracted teeth, NCSC can be obtained from the palate, which represents a large stem cell reservoir in the mucosa.